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EhBuddy Peptides

Snap-8

$61.00

EhBuddy Research-Grade Snap-8 — Research Compound

Snap-8 (Acetyl Glutamyl Heptapeptide-3) is a synthetic octapeptide analogue of SNAP-25 — a key SNARE complex protein involved in neurotransmitter vesicle release at the neuromuscular junction. Research demonstrates Snap-8 competitively inhibits the SNARE complex assembly, reducing acetylcholine release and muscle contraction amplitude — making it the most studied peptide for neuromuscular junction research and wrinkle relaxation biology.

Reconstitution: Bacteriostatic Water (BAC Water) or Sterile Water required.

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.

Free shipping on Canadian orders over $350

20 in stock (can be backordered)

Description

Snap-8 — SNARE Complex Inhibitor | Neuromuscular Junction Research

Snap-8 (Acetyl-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂) is a synthetic octapeptide analogue of the N-terminal segment of SNAP-25 (Synaptosomal-Associated Protein 25kDa) — one of three SNARE proteins required for neurotransmitter vesicle docking and fusion at the neuromuscular junction. By mimicking this segment, Snap-8 competitively displaces SNAP-25 from the SNARE complex, interfering with acetylcholine vesicle release and thereby modulating neuromuscular transmission amplitude.


Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.

Key Research Areas

🧬 SNARE Complex Biology Research

The SNARE complex (Syntaxin, SNAP-25, VAMP) is the fundamental machinery of neurotransmitter exocytosis throughout the nervous system. Snap-8 provides a peptide tool for studying SNARE assembly kinetics, vesicle docking requirements, and the structural basis of neurotransmitter release regulation.

⚡ Neuromuscular Junction Pharmacology

Research using Snap-8 models the pharmacology of neuromuscular transmission inhibition at a peptide level — a mechanism mechanistically related to botulinum toxin’s cleavage of SNAP-25. Snap-8 offers a reversible, dose-titratable research tool for NMJ studies.

✨ Facial Muscle Contraction Research

Snap-8 has been extensively studied in cosmetic dermatology research as a topical anti-wrinkle compound. In vitro research documents reduction in neuromuscular contraction amplitude and ex vivo skin models show reduced expression line formation — making it a reference compound in non-invasive neuromuscular dermatology research.


Why Choose EhBuddy?

  • Verified Purity — Third-party tested
  • Fast Canadian Shipping — Discreet packaging, shipped from Canada
  • Research-Grade Quality — Strict QC standards

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.

Additional information
Weight 0.05 lbs
🔬 Research Notes

⚗️ For Research Use Only. All products are intended strictly for laboratory and scientific research. Not for human or veterinary consumption.

Cosmetic peptides are studied for collagen stimulation via fibroblast activation, melanogenesis regulation through MC1R pathways, and epidermal growth factor receptor signalling. GHK-Cu is a well-documented copper peptide studied for skin remodelling.

COA

View the Certificate of Analysis (HPLC) for this product. All testing is now performed by PeakPurePeps — a local, Canadian-owned lab. If a COA for your selected batch isn’t posted yet, testing is in progress or we’re awaiting our next restock.

View this product’s COA ›
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Shipping & Delivery

Shipping & Delivery Information

Free Shipping on all orders over $350 CAD. Orders under $350 CAD are subject to a flat shipping fee.

Carriers: We ship via Canada Post Xpresspost and other couriers to ensure reliable delivery across Canada.

Estimated Delivery Times:

  • Ontario & Quebec: 1–3 business days
  • Western Canada (BC, AB, SK, MB): 2–5 business days
  • Atlantic Canada: 3–5 business days
  • Northern Territories: 5–10 business days

Packaging: All orders ship in discreet, unmarked packaging. No product names or company branding appear on the exterior.

Tracking: A tracking number will be emailed once your order ships. Most orders ship within 1 business day of payment confirmation.

Temperature-Sensitive Items: Lyophilized (freeze-dried) peptides are stable at room temperature for shipping. Store at 2–8°C upon receipt for long-term stability.

Questions? Contact us at Contact@EhBuddyPeptides.io

Disclaimer

You must be 18 or 19 years of age depending on the age of majority in your province and a licensed research professional.

All products — including research peptides and research compounds — are sold strictly for laboratory and scientific research purposes only. Not for human or veterinary consumption. No dosing instructions are provided.

We adhere to all provincial and federal laws in Canada governing Research Only Chemical sales.

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