AHK-Cu — Copper Tripeptide for Hair & Skin Research
AHK-Cu is a synthetic copper(II)-complexed tripeptide with the sequence Ala-His-Lys (Alanine-Histidine-Lysine), also known as Copper Tripeptide-3 (CAS 682809-81-0). It is structurally related to — but distinct from — the more widely studied GHK-Cu (Gly-His-Lys), and is investigated in dermatological and cosmetic peptide research as a copper carrier and signaling peptide.
Mechanism of Action
AHK-Cu is studied for delivering bioavailable copper and acting as a signaling peptide. In research models it is reported to upregulate vascular endothelial growth factor (VEGF), stimulate dermal papilla cells and microvascularization, and support collagen and extracellular-matrix production. It has no single classical receptor; copper additionally serves as an essential cofactor for lysyl oxidase (collagen/elastin cross-linking) and superoxide dismutase (antioxidant defense).
Available Formats
- 100mg
Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials refrigerated at 2–8°C, protected from light.
Key Research Areas
💇 Hair Follicle Research
Studied for stimulating dermal papilla cells and follicular vascularization via VEGF-mediated signaling, of interest in hair-loss models.
✨ Skin & Anti-Aging
Investigated for collagen and elastin synthesis and skin-firmness endpoints in dermal fibroblast research.
🩹 Wound Healing & Angiogenesis
Copper peptides are studied for promoting neovascularization and tissue repair in vitro and in vivo.
🩸 Trace-Element Delivery
Supplies bioavailable copper as a cofactor for antioxidant and matrix-remodeling enzymes.
FOR RESEARCH USE ONLY (RUO). This product is not a drug, food, or cosmetic and is not approved for human or veterinary use. All statements describe proposed or preclinical research findings only. Intended strictly for in vitro and laboratory research by qualified professionals. EhBuddy Peptides assumes no liability for misuse.
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