Retatrutide — Triple GLP-1/GIP/Glucagon Receptor Agonist
Retatrutide (LY3437943) represents the cutting edge of GLP-1 research as a triple receptor agonist acting on GLP-1, GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors simultaneously. This multi-receptor mechanism produces synergistic metabolic effects that exceed those of dual or single agonists. EhBuddy offers research-grade Retatrutide across a comprehensive dosing range.
Available Formats
- 5mg
- 10mg
- 15mg
- 20mg
- 30mg
- 40mg
- 50mg
- 60mg
Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.
Key Research Areas
⚡ Unprecedented Weight Loss in Research Models
Phase 2 clinical research demonstrated up to 24% body weight reduction over 48 weeks — the highest ever recorded for a GLP agonist compound at time of study. Research models consistently show superior fat mass reduction compared to dual agonists like Tirzepatide.
🩸 Blood Glucose & Metabolic Regulation
Triple agonism drives powerful glucose-dependent insulin secretion via GLP-1 and GIP pathways, while glucagon receptor activity promotes hepatic glucose utilization. Studies show significant HbA1c reductions in T2D research models.
🔥 Visceral Fat & Lipid Profile
Research demonstrates significant reductions in visceral adipose tissue, hepatic fat, total triglycerides, and LDL. The glucagon component specifically drives fat mobilization and thermogenesis beyond what GLP-1 alone can achieve.
❤️ Cardiovascular Research
Early data from research models suggests potential cardiovascular benefits including improved blood pressure, endothelial function, and inflammatory markers — consistent with other GLP-1 class compounds but with amplified effect.
🧬 NASH / Liver Research
Glucagon receptor agonism combined with GLP-1 produces compelling reductions in hepatic steatosis markers, making Retatrutide a leading compound of interest in NASH and metabolic liver disease research.
Why Choose EhBuddy?
- ✅ Verified Purity — Third-party tested for identity and potency
- ✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
- ✅ Research-Grade Quality — Strict quality-control manufacturing standards
- ✅ Widest Dose Range Available — 5mg through 60mg for all research protocols
FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only. EhBuddy Peptides assumes no liability for misuse.
Alicia N. –
Quality appears excellent. Shipping took 4 days to Alberta which is fine. The bac water from EhBuddy worked great for reconstitution. Repurchasing for sure.
Tyler H. –
Very impressed. Retatrutide is hard to find at this purity level in Canada. Both vials reconstituted cleanly, no floaters. Tracking provided same-day. EhBuddy gets it.
Michael N. –
I have been using this Reta for almost a year, been buying larger sizes as my dose went up but i have no complaints