Name: GLP-1
SKU: PEP-GLP-1
Price: 127.00 CAD
Availability: BackOrder

GLP-1

$127.00

EhBuddy Research-Grade GLP-1 (Glucagon-Like Peptide-1) — Research Compound

GLP-1 (7-36 amide) is the endogenous incretin hormone produced by intestinal L-cells in response to food intake — the native peptide target of the entire GLP-1 receptor agonist drug class. As a research tool, native GLP-1 enables study of incretin physiology, GLP-1 receptor biology, and serves as the reference standard for all GLP-1 receptor agonist research compounds including Semaglutide, Tirzepatide, and Retatrutide.

Reconstitution: Bacteriostatic Water (BAC Water) or Sterile Water required.

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.

Free shipping on Canadian orders over $350

⏱ On Backorder — Estimated dispatch within 8 business days for most backorders. Shipping notification sent by email once dispatched.

Available on backorder

Description

GLP-1 (7-36 Amide) — Native Incretin Hormone | GLP-1 Receptor Research

GLP-1 (Glucagon-Like Peptide-1, 7-36 amide) is the endogenous incretin hormone cleaved from proglucagon by intestinal L-cells in the ileum and colon in response to nutrient ingestion. It acts on GLP-1 receptors (GLP-1R) throughout the body — on pancreatic beta cells to enhance insulin secretion, on the hypothalamus to reduce appetite, on the vagus nerve to slow gastric emptying, and on the heart for cardioprotective effects. Native GLP-1 has a plasma half-life of ~2 minutes due to rapid DPP-4 degradation — the challenge that long-acting analogues (Semaglutide, Liraglutide) were engineered to overcome.

Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.

Key Research Areas

⚡ Incretin Physiology Reference Standard

Native GLP-1 is the essential reference compound for understanding incretin biology. Research using GLP-1 establishes baseline receptor responses, pharmacokinetic benchmarks, and physiological signalling dynamics against which all synthetic analogues are compared.

🩸 Glucose-Dependent Insulin Secretion

GLP-1 enhances insulin secretion only in the presence of elevated glucose — the basis of its safety profile in the entire GLP-1 drug class. Research using native GLP-1 defines the glucose-dependency thresholds and beta cell signalling mechanisms underlying this key pharmacological property.

🧠 Central Appetite Regulation Research

GLP-1R is expressed in the hypothalamic arcuate and paraventricular nuclei. Research using native GLP-1 maps the central satiety circuits, vagal afferent pathways, and appetite neuroscience downstream of GLP-1R activation.

🔬 GLP-1R Binding & Signalling Research

Native GLP-1 is the reference ligand for all GLP-1 receptor binding assays, SAR (structure-activity relationship) studies, and receptor pharmacology research comparing endogenous vs. synthetic GLP-1R agonists.

Why Choose EhBuddy?

✅ Verified Purity — Third-party tested
✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
✅ Research-Grade Quality — Strict QC standards

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.

Additional information

Weight	0.05 lbs

🔬 Research Notes

⚗️ For Research Use Only. All products are intended strictly for laboratory and scientific research. Not for human or veterinary consumption.

GLP-1 receptor agonists are studied in metabolic research for glucose-dependent insulin secretion, glucagon suppression, gastric emptying modulation, and hypothalamic appetite regulation. Multi-receptor agonist compounds (GLP-1/GIP/glucagon) are an active research area for additive effects on energy expenditure and adipose tissue reduction.

COA

View the Certificate of Analysis (HPLC) for this product. All testing is now performed by PeakPurePeps — a local, Canadian-owned lab. If a COA for your selected batch isn’t posted yet, testing is in progress or we’re awaiting our next restock.

View this product’s COA ›

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Shipping & Delivery

Shipping & Delivery Information

Free Shipping on all orders over $350 CAD. Orders under $350 CAD are subject to a flat shipping fee.

Carriers: We ship via Canada Post Xpresspost and other couriers to ensure reliable delivery across Canada.

Estimated Delivery Times:

Ontario & Quebec: 1–3 business days
Western Canada (BC, AB, SK, MB): 2–5 business days
Atlantic Canada: 3–5 business days
Northern Territories: 5–10 business days

Packaging: All orders ship in discreet, unmarked packaging. No product names or company branding appear on the exterior.

Tracking: A tracking number will be emailed once your order ships. Most orders ship within 1 business day of payment confirmation.

Temperature-Sensitive Items: Lyophilized (freeze-dried) peptides are stable at room temperature for shipping. Store at 2–8°C upon receipt for long-term stability.

Questions? Contact us at Contact@EhBuddyPeptides.io

Disclaimer

You must be 18 or 19 years of age depending on the age of majority in your province and a licensed research professional.

All products — including research peptides and research compounds — are sold strictly for laboratory and scientific research purposes only. Not for human or veterinary consumption. No dosing instructions are provided.

We adhere to all provincial and federal laws in Canada governing Research Only Chemical sales.

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GLP-1