AOD9604 — HGH Fragment 177-191 | Targeted Fat Loss Research
AOD9604 (Anti-Obesity Drug 9604) is a stabilized synthetic peptide corresponding to the C-terminal fragment of Human Growth Hormone (amino acids 177–191) with a tyrosine addition at the N-terminus for stability. This specific HGH fragment has been identified as responsible for GH’s lipolytic activity, completely isolated from GH’s growth-promoting and insulin-desensitizing effects. Monash University research established AOD9604 as a selective fat-targeting compound — and it received GRAS (Generally Recognized As Safe) designation from the FDA.
Available Format: 5mg per vial (10 vials)
Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.
Key Research Areas
🔥 Selective Lipolysis Stimulation
AOD9604 stimulates lipolysis (fat breakdown) via beta-3 adrenergic receptor-like mechanisms, mimicking GH’s fat-mobilizing signal without activating IGF-1 or GH receptor-mediated growth pathways. Research demonstrates dose-dependent fat mass reduction in obese animal models.
🚫 Lipogenesis Inhibition
AOD9604 inhibits de novo lipogenesis (new fat synthesis) independently of caloric intake. Research shows simultaneous fat burning stimulation + fat synthesis blockade — a dual fat loss mechanism not shared by other GH fragments.
🩸 Metabolic Safety Profile
FDA GRAS designation reflects AOD9604’s exceptional safety profile. Unlike full HGH, AOD9604 does not elevate IGF-1, glucose, or insulin resistance. Clinical Phase 2 research confirmed safety across multiple dose levels in human obesity research subjects.
🔬 Chondroprotective Research
Unexpected research findings showed AOD9604 has potential chondroprotective effects — stimulating cartilage growth factor expression and potentially offering applications in osteoarthritis research beyond its fat-loss profile.
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- ✅ Verified Purity — Third-party tested for identity and potency
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FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.
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