Bronchogen

Bronchogen — Bronchopulmonary Peptide Bioregulator

Bronchogen is a short synthetic peptide bioregulator with the sequence Ala-Asp-Glu-Leu (ADEL). It belongs to the Khavinson family of tissue-specific “cytomax/cytogen” peptides developed to study regulation of gene expression in respiratory tissue. In preclinical research it is investigated for its proposed role in bronchial epithelial homeostasis and repair.

Mechanism of Action

As an ultrashort peptide bioregulator of the Khavinson class, Bronchogen is studied for a non-receptor, epigenetic-style mechanism. The peptide is small enough to be proposed to cross the cell and nuclear membranes and interact directly with DNA and chromatin, modulating the tissue-specific expression of genes associated with bronchial and pulmonary cells. This differs fundamentally from receptor-signaling peptides — the proposed activity is regulation of transcription rather than activation of a cell-surface receptor. Evidence is preclinical (cell-culture and animal models) from the originating research program.

Available Formats

• 20mg

Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials refrigerated at 2–8°C, protected from light.

Key Research Areas

🫁 Bronchial Epithelial Regeneration

In airway-damage models, Bronchogen is studied for restoration of ciliated-cell populations and epithelial differentiation of the bronchial lining.

🫁 Respiratory Gene Expression

Investigated for influence on lung-lineage transcription factors (such as NKX2-1 and FOXA1/2) and mucin/surfactant-associated genes in experimental systems.

🫁 Respiratory Inflammation

Associated in preclinical work with reduced neutrophilic inflammation and normalized immune-cell profiles in respiratory tissue.

⏳ Respiratory Tissue Aging

Studied within the peptide-bioregulator program for age-related changes in pulmonary tissue.

FOR RESEARCH USE ONLY (RUO). This product is not a drug, food, or cosmetic and is not approved for human or veterinary use. All statements describe proposed or preclinical research findings only. Intended strictly for in vitro and laboratory research by qualified professionals. EhBuddy Peptides assumes no liability for misuse.