Vitamin B12 (Methylcobalamin)

Vitamin B12 (Methylcobalamin) — Bioactive Coenzyme Form for Research

Methylcobalamin is the bioactive, coenzyme form of vitamin B12 (as opposed to synthetic cyanocobalamin), supplied here as a ready-to-use 10ml solution at 100mg/ml (1g total per vial). It is a deep red, light-sensitive compound used in cellular energy, methylation and neurological research.

Mechanism of Action

Methylcobalamin is the required cofactor for methionine synthase, which converts homocysteine to methionine and regenerates the folate cycle. This drives cellular methylation reactions — of DNA, proteins and neurotransmitters — via S-adenosylmethionine (SAMe), and helps regulate homocysteine. Its cobalamin cofactors also support fatty-acid and amino-acid metabolism feeding mitochondrial energy pathways.

Format

• 10ml ready-to-use solution (100mg/ml)

Handling: No reconstitution required. Methylcobalamin is light-sensitive — keep protected from light and refrigerated at 2–8°C.

Key Research Areas

⚡ Methylation & One-Carbon Metabolism

Studied as the cofactor for methionine synthase in homocysteine regulation and SAMe-dependent methylation reactions.

⚡ Energy Metabolism

Essential to normal cellular energy production and red-blood-cell formation; deficiency models present with fatigue and megaloblastic anemia.

🧠 Neurological Support

Critical for myelin-sheath synthesis and normal nerve conduction; studied in neuropathy, nerve-regeneration and cognitive research contexts.

🔬 Homocysteine Regulation

Investigated for its role in lowering homocysteine via remethylation to methionine.

FOR RESEARCH USE ONLY (RUO). This product is not a drug, food, or cosmetic and is not approved for human or veterinary use. All statements describe proposed or preclinical research findings only. Intended strictly for in vitro and laboratory research by qualified professionals. EhBuddy Peptides assumes no liability for misuse.