Vasoactive Intestinal Peptide (VIP) — Neuropeptide Immunomodulator | Research
VIP is a 28-amino-acid neuropeptide widely distributed throughout the central and peripheral nervous system, GI tract, respiratory system, and immune tissues. Acting through VPAC1, VPAC2, and PAC1 receptors, VIP exerts diverse biological effects spanning vasodilation, gut motility regulation, circadian rhythm control, immune suppression, and neuroprotection — making it one of the most pleiotropic neuropeptides available for research.
Available Formats
- 10mg
- 5mg
Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.
Key Research Areas
🛡️ Potent Anti-Inflammatory & Immunomodulatory
VIP is a powerful endogenous anti-inflammatory molecule. Research demonstrates VIP inhibits macrophage and DC activation, reduces TNF-α, IL-6, IL-1β, and IL-12 production, and shifts immune responses toward Th2/Treg profiles — applicable to autoimmune disease, sepsis, and chronic inflammation research models.
🫁 Pulmonary Vasodilation Research
VIP is a potent pulmonary vasodilator and bronchodilator. Research in pulmonary arterial hypertension (PAH) models shows significant pressure reduction. VIP inhalation has been studied clinically for PAH treatment.
🕐 Circadian Rhythm Research
VIP is a primary neurotransmitter of the suprachiasmatic nucleus (SCN) — the brain’s master circadian clock. Research uses VIP to study circadian synchronization, jet lag models, seasonal affective disorder, and sleep-wake cycle regulation.
🫀 GI Motility & Gut Research
VIP regulates intestinal smooth muscle relaxation, secretion, and enteric nervous system function. Research applications span IBS, IBD, gut dysmotility, and intestinal barrier integrity studies.
Why Choose EhBuddy?
- ✅ Verified Purity — Third-party tested
- ✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
- ✅ Research-Grade Quality — Strict QC standards
FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.













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