PNC-27 (5mg) — Selective Anticancer Peptide | Oncology Research
PNC-27 (5mg) — the research entry vial of this innovative chimeric anticancer peptide. PNC-27 combines the p53 MDM2-binding domain with a membrane-penetrating leader sequence to selectively target HDM-2-expressing cancer cells for direct membrane lysis. The 5mg format is ideal for in vitro cytotoxicity assays, cancer cell line screening, and preliminary mechanism-of-action studies.
Available Format: 5mg lyophilized vial
Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.
Key Research Areas
🏥 In Vitro Cancer Cell Selectivity Research
The 5mg format enables comprehensive cancer cell line screening panels — testing PNC-27’s selective activity against HDM-2-expressing cancer lines (pancreatic, breast, melanoma, leukemia, colon) alongside normal cell controls to confirm the selectivity profile documented in published research.
🔬 Membrane Lysis Mechanism Studies
At 5mg scale, mechanistic studies using electron microscopy, membrane permeability assays, and live-cell imaging can characterize PNC-27’s pore-forming activity and membrane disruption kinetics in specific cancer cell types.
🧬 Dose-Response Research
The 5mg vial supports IC50 determination across multiple cell lines, enabling systematic dose-response research needed to characterize PNC-27’s research profile before scaling to larger studies.
Why Choose EhBuddy?
- ✅ Verified Purity — Third-party tested
- ✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
- ✅ Research-Grade Quality — Strict QC standards
FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.
Reviews
There are no reviews yet.