Name: Ara-290
SKU: RA10
Price: 62.00 CAD
Availability: BackOrder

Ara-290

$62.00

EhBuddy Research-Grade Ara-290 (Cibinetide) — Research Compound

Ara-290 (Cibinetide) is a synthetic 11-amino-acid peptide derived from the innate repair receptor (IRR) binding domain of EPO — retaining EPO’s tissue-protective properties without erythropoietic activity. Research demonstrates potent anti-inflammatory, neuroprotective, and metabolic effects via the beta-common receptor — with Phase 2 clinical data in neuropathy and sarcoidosis.

Reconstitution: Bacteriostatic Water (BAC Water) or Sterile Water required.

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.

⏱ On Backorder — Estimated dispatch within 8 business days for most backorders. Shipping notification sent by email once dispatched.

Available on backorder

Description

Ara-290 (Cibinetide) — Non-Erythropoietic EPO Peptide | Neuroprotection Research

Ara-290 (Cibinetide, ARA 290) is a synthetic 11-amino-acid helix B surface peptide (HBSP) derived from the tissue-protective domain of erythropoietin — specifically the helix B region that binds the innate repair receptor (IRR, a β-common receptor heterodimer distinct from the classical erythropoietin receptor). By targeting the IRR rather than EPOR, Ara-290 produces EPO’s tissue-protective and anti-inflammatory effects without erythropoiesis, hematopoietic side effects, or thromboembolic risk.

Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.

Key Research Areas

🧠 Neuroprotection & Peripheral Neuropathy Research

Phase 2 clinical trial in sarcoidosis-associated small-fiber neuropathy demonstrated Ara-290 improved corneal nerve fiber density and neuropathic symptoms. Research shows nerve fiber regeneration and protection via IRR signalling in peripheral nerve injury models.

🩸 Anti-Inflammatory Without Erythropoiesis

Ara-290 potently suppresses inflammatory cytokines (TNF-α, IL-1β, IL-6) via IRR/β-common receptor signalling without any effect on red blood cell production — enabling EPO’s anti-inflammatory pathways to be studied in isolation from haematopoietic biology.

🩺 Metabolic & Pancreatic Research

IRR is expressed on pancreatic islet cells. Ara-290 research shows protection of beta cells from inflammatory and oxidative damage, improved insulin secretion, and potential applications in T1D and T2D protection research models.

❤️ Cardiac & Organ Protection

IRR-mediated cytoprotection extends to cardiac, renal, and hepatic tissue. Research in ischemia models shows significant Ara-290-mediated organ protection — consistent with EPO’s tissue-protective role but without hematological side effects.

Why Choose EhBuddy?

✅ Verified Purity — Third-party tested
✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
✅ Research-Grade Quality — Strict QC standards

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.

Additional information

Weight	0.1 lbs

🔬 Research Notes

⚗️ For Research Use Only. All products are intended strictly for laboratory and scientific research. Not for human or veterinary consumption.

Tissue repair peptides such as BPC-157 and TB-500 are studied for angiogenesis, fibroblast proliferation, collagen synthesis, tendon and ligament repair, and wound healing mechanisms. Research includes nitric oxide production and anti-inflammatory cytokine modulation.

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Shipping & Delivery

Shipping & Delivery Information

Free Shipping on all orders over $350 CAD. Orders under $350 CAD are subject to a flat shipping fee.

Carriers: We ship via Canada Post Xpresspost and other couriers to ensure reliable delivery across Canada.

Estimated Delivery Times:

Ontario & Quebec: 1–3 business days
Western Canada (BC, AB, SK, MB): 2–5 business days
Atlantic Canada: 3–5 business days
Northern Territories: 5–10 business days

Packaging: All orders ship in discreet, unmarked packaging. No product names or company branding appear on the exterior.

Tracking: A tracking number will be emailed once your order ships. Most orders ship within 1 business day of payment confirmation.

Temperature-Sensitive Items: Lyophilized (freeze-dried) peptides are stable at room temperature for shipping. Store at 2–8°C upon receipt for long-term stability.

Questions? Contact us at Contact@EhBuddyPeptides.io

Disclaimer

You must be 18 or 19 years of age depending on the age of majority in your province and a licensed research professional.

All products — including research peptides, injectable steroids (testosterone, nandrolone, boldenone, trenbolone, etc.), oral steroids, and oral research compounds — are sold strictly for laboratory and scientific research purposes only. Not for human or veterinary consumption. No dosing instructions are provided.

We adhere to all provincial and federal laws in Canada governing Research Only Chemical sales.

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Ara-290