Epitalon (Epithalon) — Telomerase Activator | Longevity & Anti-Aging Research
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide analogue of Epithalamin — the natural polypeptide fraction of the pineal gland with documented aging-regulatory effects. Pioneered by Russian gerontologist Professor Vladimir Khavinson over 40+ years of research, Epitalon represents one of the most studied longevity peptides in existence, with data across telomere biology, circadian regulation, cancer resistance, and lifespan extension.
Available Formats
- 10mg
- 50mg
Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.
Key Research Areas
🧬 Telomerase Activation & Telomere Elongation
Epitalon is the first and most studied peptide to demonstrate telomerase activation in somatic cells. Research shows Epitalon induces telomere elongation in aged human cells in vitro and in animal models — directly addressing the cellular aging mechanism. This remains the central focus of Epitalon longevity research.
🌙 Melatonin & Circadian Research
Epitalon regulates pineal melatonin production — normalizing age-related melatonin decline. Research demonstrates restoration of circadian rhythm amplitude, improved sleep architecture, and synchronization of biological clocks in aged animal models.
⚡ Lifespan Extension Research
Studies in fruit flies, mice, and rats show Epitalon extends maximum lifespan by 13–25% compared to controls. The mechanism involves both telomere maintenance and cancer resistance — Epitalon-treated animals develop fewer spontaneous tumors at significantly later ages.
🛡️ Cancer Research
Epitalon demonstrates anti-tumor effects in animal models — reducing tumor frequency, delaying tumor onset, and inhibiting tumor growth via normalization of neuroendocrine function and cell cycle regulation.
👁️ Retinal & Neurological Research
Research documents Epitalon’s protective effects on retinal photoreceptors and its potential in age-related macular degeneration models — an active area of ophthalmic aging research.
Why Choose EhBuddy?
- ✅ Verified Purity — Third-party tested
- ✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
- ✅ Research-Grade Quality — Strict QC standards
FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.













Frank D. –
Epitalon quality here is excellent. One of my core anti-aging research compounds. EhBuddy ships discreetly and fast. Already on my third order.