MOTS-C

EhBuddy Research-Grade MOTS-c — Available in 10mg, 40mg

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a mitochondria-derived peptide that regulates metabolic homeostasis, insulin sensitivity, and exercise mimicry. Research demonstrates MOTS-c activates AMPK, improves glucose uptake, reduces age-related metabolic decline, and may function as a mitochondria-to-nucleus signalling molecule — a fundamentally novel biological mechanism.

Reconstitution: Bacteriostatic Water (BAC Water) or Sterile Water required.

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only. EhBuddy Peptides assumes no liability for misuse.

Description

MOTS-c — Mitochondrial-Derived Peptide | Metabolic & Longevity Research

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a recently discovered 16-amino-acid peptide encoded within the mitochondrial genome — making it one of the most biologically novel peptides in research today. MOTS-c translocates from mitochondria to the nucleus in response to metabolic stress, where it modulates gene expression and restores metabolic homeostasis. Research in aging and metabolic models has generated exceptional interest in this compound as a longevity and metabolic research tool.

Available Formats

10mg
40mg

Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.

Key Research Areas

⚡ AMPK Activation & Exercise Mimicry

MOTS-c activates AMPK (AMP-activated protein kinase) — the master regulator of cellular energy homeostasis. Research shows MOTS-c mimics exercise benefits in animal models, improving physical performance, endurance capacity, and metabolic flexibility without exercise.

🩸 Insulin Sensitivity & Glucose Metabolism

Studies demonstrate MOTS-c improves insulin sensitivity, increases glucose uptake in muscle tissue, and reduces fat accumulation in insulin-resistant research models. This positions MOTS-c as a research compound of interest for type 2 diabetes and metabolic syndrome.

🧬 Longevity & Aging Research

MOTS-c levels decline with age in humans, and research in animal models shows exogenous MOTS-c extends lifespan and improves age-related metabolic function. Its mitochondria-nucleus signalling role suggests a fundamental role in mitochondrial-nuclear crosstalk research.

🔥 Fat Loss & Body Composition

Research models show MOTS-c promotes fat oxidation, reduces visceral adiposity, and improves body composition independently of caloric restriction — a finding of significant interest in metabolic research.

💪 Physical Performance Research

Mouse models show MOTS-c injection dramatically improves treadmill endurance and grip strength in aged animals — restoring youthful performance metrics in aged research subjects.

Why Choose EhBuddy?

✅ Verified Purity — Third-party tested for identity and potency
✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
✅ Research-Grade Quality — Strict manufacturing quality standards

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only. EhBuddy Peptides assumes no liability for misuse.

Additional information

Weight	0.1 lbs

🔬 Research Notes

⚗️ For Research Use Only. All products are intended strictly for laboratory and scientific research. Not for human or veterinary consumption.

Longevity peptides including Epitalon, Thymalin, and pineal-derived compounds are studied for telomere length modulation, melatonin regulation, and thymic function restoration. NAD+ precursors and mitochondria-targeted compounds (SS-31, MOTS-C) are studied for mitochondrial biogenesis and oxidative stress reduction.

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Shipping & Delivery

Shipping & Delivery Information

Free Shipping on all orders over $350 CAD. Orders under $350 CAD are subject to a flat shipping fee.

Carriers: We ship via Canada Post Xpresspost and other couriers to ensure reliable delivery across Canada.

Estimated Delivery Times:

Ontario & Quebec: 1–3 business days
Western Canada (BC, AB, SK, MB): 2–5 business days
Atlantic Canada: 3–5 business days
Northern Territories: 5–10 business days

Packaging: All orders ship in discreet, unmarked packaging. No product names or company branding appear on the exterior.

Tracking: A tracking number will be emailed once your order ships. Most orders ship within 1 business day of payment confirmation.

Temperature-Sensitive Items: Lyophilized (freeze-dried) peptides are stable at room temperature for shipping. Store at 2–8°C upon receipt for long-term stability.

Questions? Contact us at Contact@EhBuddyPeptides.io

Disclaimer

You must be 18 or 19 years of age depending on the age of majority in your province and a licensed research professional.

All products — including research peptides, injectable steroids (testosterone, nandrolone, boldenone, trenbolone, etc.), oral steroids, and oral research compounds — are sold strictly for laboratory and scientific research purposes only. Not for human or veterinary consumption. No dosing instructions are provided.

We adhere to all provincial and federal laws in Canada governing Research Only Chemical sales.

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