Thymosin Alpha-1 (Tα1) — Approved Immune Modulator | Research Grade
Thymosin Alpha-1 is the N-terminally acetylated 28-amino-acid peptide derived from prothymosin alpha — one of the thymic hormones responsible for T-cell maturation and immune competence. Available commercially as Zadaxin® with regulatory approval in 30+ countries (Italy, China, and others) for hepatitis B, hepatitis C, non-small cell lung cancer, and malaria immunotherapy, Thymosin Alpha-1 has one of the richest clinical evidence bases of any research peptide.
Available Formats
- 5mg
- 10mg
Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.
Key Research Areas
🛡️ Innate & Adaptive Immune Activation
Tα1 activates toll-like receptor (TLR) 9 signalling on dendritic cells and plasmacytoid DCs, driving type I interferon production and Th1 immune polarization. Research demonstrates enhanced NK cell function, CD8+ T-cell activation, and dendritic cell maturation — boosting both innate and adaptive immunity.
🦠 Antiviral Research (Hepatitis B/C)
Approved clinical evidence demonstrates Tα1’s ability to reduce viral load, improve seroconversion rates, and enhance interferon efficacy in hepatitis B and C research models. These Phase 3 trial data provide the highest quality evidence available for any thymic peptide.
🏥 Sepsis & Critical Illness Research
Recent research has explored Tα1 in sepsis models — where immune exhaustion and immunoparalysis dramatically worsen outcomes. Studies show Tα1 reverses immune exhaustion, improves 28-day survival rates, and restores T-cell function in sepsis research models.
🧬 Cancer Immunotherapy Research
Tα1 enhances the efficacy of checkpoint inhibitors, vaccines, and conventional cancer therapies via immune system upregulation. Research spans multiple cancer models including lung, colon, and hepatocellular carcinoma.
Why Choose EhBuddy?
- ✅ Verified Purity — Third-party tested
- ✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
- ✅ Research-Grade Quality — Strict QC standards
- ✅ Clinical-Grade Evidence — Approved in 30+ countries under the trade name Zadaxin®
FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.













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