1-bioglutide — Novel GLP-4 Quadruple Agonist for Metabolic Research
1-bioglutide (also known as NA-931 or Bioglutide, developed by Biomed Industries) is a novel investigational multi-agonist peptide, informally described as a “GLP-4” quadruple agonist. It is a clinical-stage compound not broadly available through established peptide channels, of research interest for layering incretin and anabolic signaling in a single molecule.
Mechanism of Action
Unlike single, dual, or triple incretin agonists, 1-bioglutide is reported to engage four targets simultaneously: the GLP-1 receptor, the GIP receptor, the glucagon receptor (GCGR), and — distinctively — the IGF-1 receptor. The incretin arms are studied for appetite suppression and glucose-dependent insulin response, while the IGF-1 receptor arm is of particular interest for countering the lean-mass loss associated with pure GLP-1 agonists.
Available Formats
- 5mg
- 10mg
Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials refrigerated at 2–8°C, protected from light.
Key Research Areas
⚡ Weight-Regulation Research
GLP-1-driven hypothalamic satiety signaling and appetite suppression are studied for body-weight regulation.
⚡ Glycemic Research
GIP-enhanced glucose-dependent insulin response is investigated in metabolic models.
🔥 Lean-Mass Preservation
The IGF-1 receptor arm is studied for maintaining lean mass alongside fat reduction — a differentiator from single GLP-1 agonists.
🩸 Subcutaneous Delivery
Supplied as a lyophilized powder for reconstitution with bacteriostatic or sterile water and subcutaneous administration in research models — the same delivery route used for established GLP-1 and multi-agonist research peptides. This is an injectable research compound, not an oral formulation.
FOR RESEARCH USE ONLY (RUO). This product is not a drug, food, or cosmetic and is not approved for human or veterinary use. All statements describe proposed or preclinical research findings only. Intended strictly for in vitro and laboratory research by qualified professionals. EhBuddy Peptides assumes no liability for misuse.
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