Adamax

Adamax — Adamantane-Modified Semax Analog (Nootropic Research Peptide)

Adamax is a synthetic research peptide — an adamantane-modified, N-acetylated analog of Semax (Acetyl-Semax-Adamantane), with a molecular weight of approximately 1032 Da. Semax is itself a synthetic analog of the ACTH(4-10) fragment of adrenocorticotropic hormone; Adamax adds an N-terminal acetyl group and a lipophilic adamantane “cage” to the Semax backbone (Ac-Met-Glu-His-Phe-Pro-Gly-Pro core). Note: the “1032” seen in some listings refers to the molecular weight, not an official development code.

Mechanism of Action

Adamax’s mechanism is extrapolated from its well-studied parent Semax, as there are essentially no primary studies published under the Adamax name. Semax is documented to upregulate brain-derived neurotrophic factor (BDNF) and its TrkB receptor (and NGF) in the hippocampus, and to modulate dopamine, serotonin and norepinephrine systems. The N-acetyl and adamantyl modifications are intended to increase lipophilicity, metabolic stability and blood-brain-barrier penetration relative to native Semax, which clears within minutes.

Available Formats

• 5mg

Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials refrigerated at 2–8°C, protected from light.

Key Research Areas

🧠 Cognitive Research

Studied (via Semax read-across) for memory consolidation, learning and focus through BDNF/TrkB-driven long-term potentiation.

🧠 Neuroprotection

Investigated in ischemic/stroke and oxidative-stress models; Semax has established use in ischemic stroke research, the basis for these lines of study.

🧠 Mood & Stress Resilience

Explored for anxiolytic and mood effects via dopamine and serotonin modulation.

🧠 Neurodegeneration & TBI

Referenced in traumatic-brain-injury and neurodegenerative research models by extrapolation from Semax.

FOR RESEARCH USE ONLY (RUO). This product is not a drug, food, or cosmetic and is not approved for human or veterinary use. All statements describe proposed or preclinical research findings only. Intended strictly for in vitro and laboratory research by qualified professionals. EhBuddy Peptides assumes no liability for misuse.