Melanotan-1 Acetate (MT-1) 10mg

Melanotan-1 (MT-1, Afamelanotide) — Selective MC1R Melanogenesis Research

Melanotan-1, clinically known as Afamelanotide, is a synthetic linear analogue of α-MSH (alpha-melanocyte-stimulating hormone) with high selectivity for the MC1R receptor on melanocytes. Unlike Melanotan-2, MT-1’s linear structure confers receptor selectivity that produces strong melanogenesis with reduced MC3R/MC4R-mediated sexual and appetite effects. MT-1 holds EMA approval as Scenesse® — the only melanocortin peptide with regulatory approval — providing an exceptional research evidence base.

Available Formats

• 10mg

Reconstitution: Add 0.6% Acetic Acid first to dissolve the powder, then dilute with Bacteriostatic Water (BAC Water) or Sterile Water. Store lyophilized vials at 2–8°C.

Key Research Areas

☀️ MC1R-Selective Melanogenesis

MT-1 selectively activates MC1R on melanocytes, driving eumelanin synthesis for photoprotective, UV-resilient skin pigmentation. Research demonstrates darker, faster tanning without UV exposure and improved UV tolerance in photosensitivity research models.

🔬 Erythropoietic Protoporphyria (EPP) Research

As FDA/EMA-approved Scenesse, Afamelanotide is the gold-standard research compound for EPP — a rare disorder causing severe phototoxicity. Approval data confirms safety and efficacy in controlled trials, providing regulatory-quality research evidence for melanocortin biology.

🧬 Photoprotection Mechanism Research

MT-1 research has elucidated the molecular mechanisms of UV-induced DNA damage prevention via melanin densification, Nrf2 activation, and direct antioxidant pathways — contributing foundational knowledge to photobiology and skin cancer prevention research.

🔍 Minimal Off-Target Activity

MT-1’s receptor selectivity makes it a cleaner research tool for isolated MC1R biology compared to the non-selective MT-2, enabling precise pathway-specific research designs.

Why Choose EhBuddy?

• ✅ Verified Purity — Third-party tested for identity and potency
• ✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
• ✅ Research-Grade Quality — Strict manufacturing quality standards

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only. EhBuddy Peptides assumes no liability for misuse.