Name: Kisspeptin
SKU: kisspeptin
Availability: InStock

Kisspeptin

vials

EhBuddy Research-Grade Kisspeptin — Available in 5mg, 10mg

Kisspeptin (encoded by the KISS1 gene) is the hypothalamic neuropeptide that gates the HPG axis — acting as the master upstream regulator of GnRH pulse generation. Research demonstrates Kisspeptin activates GnRH neurons, drives LH/FSH secretion, regulates puberty onset, governs reproductive seasonality, and modulates sexual behaviour and reward. It represents the most proximal control point of the entire reproductive axis.

Reconstitution: Bacteriostatic Water (BAC Water) or Sterile Water required.

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.

Description

Kisspeptin — HPG Axis Master Regulator | Reproductive & Neuroendocrine Research

Kisspeptin (the peptide product of the KISS1 gene) is a neuropeptide released by hypothalamic KNDy neurons that acts on GnRH neurons via the GPR54/KISS1R receptor — acting as the essential gate for GnRH pulse generation and therefore the entire HPG reproductive axis. Discovered in 2003 as the key regulator of puberty initiation, Kisspeptin research has since expanded to encompass fertility, sexual behaviour, metabolic integration of reproduction, and cancer metastasis research.

Available Formats

5mg
10mg

Reconstitution: Reconstitute with Bacteriostatic Water (BAC Water) for multi-use stability, or Sterile Water for single-use protocols. Store lyophilized vials at 2–8°C.

Key Research Areas

🧬 GnRH Pulse Generation Research

Kisspeptin is the primary driver of pulsatile GnRH release from hypothalamic neurons. Research using Kisspeptin enables precise control of GnRH pulse frequency and amplitude — essential for studying pubertal timing, menstrual cycle regulation, and HPG axis dysfunction models.

🌸 Female Fertility & LH Surge Research

Kisspeptin drives the pre-ovulatory LH surge in females — the trigger for ovulation. Clinical research demonstrates intravenous Kisspeptin reliably triggers ovulation in IVF protocols with potential safety advantages over HCG in OHSS-risk patients.

💑 Sexual Behaviour & Reward Research

KISS1R activation modulates limbic and hypothalamic circuits associated with sexual motivation and reward. Research documents Kisspeptin increases attraction-related neural activity in fMRI studies and modulates sexual aversion — bridging reproductive neuroendocrinology and sexual medicine research.

🏥 Hypothalamic Amenorrhoea Research

Kisspeptin is reduced in hypothalamic amenorrhoea (stress/exercise-induced menstrual loss). Research using Kisspeptin pulse administration has restored LH pulsatility and menstrual function — providing mechanistic insight into energy-sensing control of reproduction.

Why Choose EhBuddy?

✅ Verified Purity — Third-party tested
✅ Fast Canadian Shipping — Discreet packaging, shipped from Canada
✅ Research-Grade Quality — Strict QC standards

FOR RESEARCH USE ONLY (RUO). Not approved for human or veterinary use. Intended for in vitro and laboratory research only.

Additional information

Weight	0.1 lbs

🔬 Research Notes

⚗️ For Research Use Only. All products are intended strictly for laboratory and scientific research. Not for human or veterinary consumption.

Melanocortin peptides (PT-141, MT-1, MT-2) are studied for MC3R/MC4R activation and CNS pathways involved in sexual arousal. Gonadotropin compounds (HCG, HMG, Kisspeptin, Gonadorelin) are studied for HPG axis stimulation and LH/FSH modulation.

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Shipping & Delivery

Shipping & Delivery Information

Free Shipping on all orders over $350 CAD. Orders under $350 CAD are subject to a flat shipping fee.

Carriers: We ship via Canada Post Xpresspost and other couriers to ensure reliable delivery across Canada.

Estimated Delivery Times:

Ontario & Quebec: 1–3 business days
Western Canada (BC, AB, SK, MB): 2–5 business days
Atlantic Canada: 3–5 business days
Northern Territories: 5–10 business days

Packaging: All orders ship in discreet, unmarked packaging. No product names or company branding appear on the exterior.

Tracking: A tracking number will be emailed once your order ships. Most orders ship within 1 business day of payment confirmation.

Temperature-Sensitive Items: Lyophilized (freeze-dried) peptides are stable at room temperature for shipping. Store at 2–8°C upon receipt for long-term stability.

Questions? Contact us at Contact@EhBuddyPeptides.io

Disclaimer

You must be 18 or 19 years of age depending on the age of majority in your province and a licensed research professional.

All products — including research peptides, injectable steroids (testosterone, nandrolone, boldenone, trenbolone, etc.), oral steroids, and oral research compounds — are sold strictly for laboratory and scientific research purposes only. Not for human or veterinary consumption. No dosing instructions are provided.

We adhere to all provincial and federal laws in Canada governing Research Only Chemical sales.

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