Anti-aging peptide research in Canada spans several distinct molecular approaches to studying biological aging and age-related decline. Canadian gerontology and molecular biology researchers use a range of peptide compounds to investigate telomere biology, mitochondrial function, epigenetic aging clocks, senescent cell biology, and tissue-specific regenerative signalling. This overview covers the major longevity-focused peptides currently studied in Canadian research laboratories.
Telomere and Telomerase Research
Epithalon (AEDG tetrapeptide) is the primary telomere-focused peptide studied in Canadian aging research. Research investigates whether epithalon can upregulate telomerase (TERT) expression in somatic cells, extending telomere length in cell culture models. Epithalon also modulates pineal melatonin synthesis, linking telomere biology to circadian regulation research. Canadian gerontology researchers use epithalon to study peptide-mediated telomerase activation as a research model for cellular aging.
Mitochondrial Anti-Aging Research
Mitochondrial-derived peptides MOTS-C, humanin, and SS-31 are studied in Canadian aging biology for their roles in preserving mitochondrial function across aging. MOTS-C activates AMPK and regulates nuclear gene expression in response to mitochondrial stress. Humanin protects neurons through JAK/STAT survival pathways. SS-31 targets cardiolipin to prevent mitochondrial ROS accumulation. Together these peptides provide Canadian researchers with tools to study mitochondrial aging from multiple mechanistic angles.
Senolytic Research
FOXO4-DRI peptide is studied in Canadian aging research for its ability to induce apoptosis in senescent cells by disrupting FOXO4-p53 interaction, providing a peptide-based model for targeted senescent cell clearance.
Sourcing Anti-Aging Peptides in Canada
Epithalon, MOTS-C, humanin, SS-31, and FOXO4-DRI are available from EhBuddy Peptides in Canada. For laboratory research use only.
